Multimorbidity in osteoarthritis

This review is focused on the issue of terminology in patients with multiple coexisting diseases in modern clinical practice.We articulate that multimorbidity is one of the leading problems in the field of public healthcare and that the treatment of these patients demands an integral approach derived from the combined nature of the pathology.It Foo

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Combining the Classification and Pharmacophore Approaches to Understand Homogeneous Olfactory Perceptions at Peripheral Level: Focus on Two Aroma Mixtures

The mechanisms involved in the homogeneous perception of odorant mixtures remain largely unknown.With the aim of enhancing knowledge about blending and masking mixture perceptions, we focused on structure-odor relationships by combining the classification and pharmacophore approaches.We built a dataset of about 5000 molecules and their related odor

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Reclassification of variants of uncertain significance by race, ethnicity, and ancestry for patients at risk for breast cancer

IntroductionAlthough most variants of uncertain significance (VUS) in breast cancer susceptibility genes are eventually downgraded to benign or likely benign in individuals of European ancestry, it is unclear if this also applies to non-European populations.This study examines the time to and type of VUS reclassification among a diverse cohort at r

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